R63 drops are indicated for disorders in the vast network of blood vessels (vascular disturbances), acroparesthesia (an abnormal sensation, such as tingling, numbness, pins and needles, in the hands and fingers), inflammation of blood vessel layer (endangitis), Raynaud�s disease (condition where fingers and toes feel numb and cold in response to cold temperatures or stress), cramps in calf muscles, Diseases of veins.